diff --git a/gcc/config/i386/i386.md b/gcc/config/i386/i386.md
index 2fde8cd..e9232cd 100644
--- a/gcc/config/i386/i386.md
+++ b/gcc/config/i386/i386.md
@@ -9772,9 +9772,12 @@
               (clobber (reg:CC FLAGS_REG))])
    (set (reg:CCZ FLAGS_REG) (compare:CCZ (match_dup 2) (const_int 0)))]
 {
-  operands[2] = gen_reg_rtx (TImode);
+  /* Calling force_reg may clobber operands[0].  */
+  rtx save_op0 = operands[0];
   if (!x86_64_hilo_general_operand (operands[1], TImode))
     operands[1] = force_reg (TImode, operands[1]);
+  operands[2] = gen_reg_rtx (TImode);
+  operands[0] = save_op0;
 })
 
 ;; Combine likes to form bit extractions for some tests.  Humor it.
diff --git a/gcc/testsuite/gcc.target/i386/pr106577.c b/gcc/testsuite/gcc.target/i386/pr106577.c
new file mode 100644
index 0000000..4e35031
--- /dev/null
+++ b/gcc/testsuite/gcc.target/i386/pr106577.c
@@ -0,0 +1,7 @@
+/* { dg-do compile { target int128 } } */
+/* { dg-options "-O2 -mavx" } */
+
+int i;
+void foo(void) {
+  i ^= !(((unsigned __int128)0xf0f0f0f0f0f0f0f0 << 64 | 0xf0f0f0f0f0f0f0f0) & i);
+}