diff --git a/gcc/predict.c b/gcc/predict.c
index a6769eda1c7..a7b2223c697 100644
--- a/gcc/predict.c
+++ b/gcc/predict.c
@@ -2380,6 +2380,14 @@ expr_expected_value_1 (tree type, tree op0, enum tree_code code,
 		}
 	      return NULL;
 	    }
+
+	  if (DECL_IS_MALLOC (decl))
+	    {
+	      if (predictor)
+		*predictor = PRED_MALLOC_NONNULL;
+	      return boolean_true_node;
+	    }
+
 	  if (DECL_BUILT_IN_CLASS (decl) == BUILT_IN_NORMAL)
 	    switch (DECL_FUNCTION_CODE (decl))
 	      {
diff --git a/gcc/predict.def b/gcc/predict.def
index 4ed97ed165c..8036fac84c5 100644
--- a/gcc/predict.def
+++ b/gcc/predict.def
@@ -169,6 +169,9 @@ DEF_PREDICTOR (PRED_HOT_LABEL, "hot label", HITRATE (85), 0)
 DEF_PREDICTOR (PRED_COLD_LABEL, "cold label", PROB_VERY_LIKELY,
 	       PRED_FLAG_FIRST_MATCH)
 
+/* Return value of malloc function is almost always non-null.  */
+DEF_PREDICTOR (PRED_MALLOC_NONNULL, "malloc returned non-NULL", \
+	       PROB_VERY_LIKELY, PRED_FLAG_FIRST_MATCH)
 
 /* The following predictors are used in Fortran. */
 
diff --git a/gcc/testsuite/gcc.dg/predict-16.c b/gcc/testsuite/gcc.dg/predict-16.c
new file mode 100644
index 00000000000..3a3e943bb79
--- /dev/null
+++ b/gcc/testsuite/gcc.dg/predict-16.c
@@ -0,0 +1,31 @@
+/* { dg-do compile } */
+/* { dg-options "-O2 -fdump-tree-profile_estimate" } */
+
+#include <stdlib.h>
+#include <string.h>
+
+void *r;
+void *r2;
+void *r3;
+void *r4;
+
+void *m (size_t s, int c)
+{
+  r = malloc (s);
+  if (r)
+    memset (r, 0, s);
+
+  r2 = calloc (s, 0);
+  if (r2)
+    memset (r2, 0, s);
+
+  r3 = __builtin_malloc (s);
+  if (r3)
+    memset (r3, 0, s);
+
+  r4 = __builtin_calloc (s, 0);
+  if (r4)
+    memset (r4, 0, s);
+}
+
+/* { dg-final { scan-tree-dump-times "malloc returned non-NULL heuristics of edge\[^:\]*: 99.96%" 4 "profile_estimate"} } */